Molecular players in biogenesis of mineralization-competent matrix vesicles
نویسندگان
چکیده
منابع مشابه
Regulated Production of Mineralization-competent Matrix Vesicles in Hypertrophic Chondrocytes
Matrix vesicles have a critical role in the initiation of mineral deposition in skeletal tissues, but the ways in which they exert this key function remain poorly understood. This issue is made even more intriguing by the fact that matrix vesicles are also present in nonmineralizing tissues. Thus, we tested the novel hypothesis that matrix vesicles produced and released by mineralizing cells ar...
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PHOSPHO1 is a phosphoethanolamine/phosphocholine phosphatase that has previously been implicated in generating inorganic phosphate (P(i)) for matrix mineralization. In this study, we have investigated PHOSPHO1 mRNA expression during embryonic development in the chick. Whole-mount in situ hybridization indicated that PHOSPHO1 expression occurred prior to E6.5 and was initially restricted to the ...
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ژورنال
عنوان ژورنال: Bone Reports
سال: 2020
ISSN: 2352-1872
DOI: 10.1016/j.bonr.2020.100435